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Rapid detection of allelic losses in brain tumours using microsatellite repeat markers and high-performance liquid chromatography

High-performance liquid chromatography (HPLC) is a recently introduced high-capacity automated method for detecting unknown mutations (denaturing HPLC) or for sizing DNA fragments under nondenaturing conditions. We have adapted the HPLC method for detection of loss of heterozygosity (LOH) and used g...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chernova, O B, Barnett, G H, Cowell, J K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741124/
https://ncbi.nlm.nih.gov/pubmed/12799632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601025
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