Mutations in the ST7/RAY1/HELG locus rarely occur in primary colorectal, gastric, and hepatocellular carcinomas

Human cancers frequently show a loss of heterozygosity on chromosome 7q31, which indicates the existence of broad-range tumour-suppressor gene(s) at this locus. Truncating mutations in the ST7 gene at this locus are seen frequently in primary colon cancer and breast cancer cell lines. Therefore, the...

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Detalhes bibliográficos
Main Authors: Yoshimura, S, Yamada, T, Ohwada, S, Koyama, T, Hamada, K, Tago, K, Sakamoto, I, Takeyoshi, I, Ikeya, T, Makita, F, Iino, Y, Morishita, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741100/
https://ncbi.nlm.nih.gov/pubmed/12799635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600942
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