Pharmacodynamic characterization of insulin on MDMA-induced thermogenesis

Sympathomimetic drugs (MDMA; Ecstasy) induce a potentially catastrophic hyperthermia that involves free fatty acid (FFA) activation of mitochondrial uncoupling proteins (UCP). Insulin is an important regulator of plasma FFA levels, although its role in thermogenesis is unclear. The aims of the prese...

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Bibliografiske detaljer
Main Authors: Banks, Matthew L., Buzard, Sarah K., Gehret, Candice M., Monroy, Alexa L., Kenaston, M. Alex, Mills, Edward M., Sprague, Jon E.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740838/
https://ncbi.nlm.nih.gov/pubmed/19482019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2009.05.021
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