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How to Switch Off a Histidine Kinase: Crystal Structure of Geobacillus stearothermophilus KinB with the inhibitor Sda
Entry to sporulation in Bacilli is governed by a histidine kinase phosphorelay, a variation on the predominant signal transduction mechanism in prokaryotes. Sda directly inhibits sporulation histidine kinases in response to DNA damage and replication defects. We determined a 2.0 Å-resolution X-ray c...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740816/ https://ncbi.nlm.nih.gov/pubmed/19101565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.12.006 |
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