Intestinal Anion Exchanger Down-regulated in Adenoma (DRA) Is Inhibited by Intracellular Calcium

The Na/H exchanger 3 (NHE3) and the Cl/HCO(3) exchanger down-regulated in adenoma (DRA) together facilitate intestinal electroneutral NaCl absorption. Elevated Ca(2+)(i) inhibits NHE3 through mechanisms involving the PDZ domain proteins NHE3 kinase A regulatory protein (E3KARP) or PDZ kidney 1 (PDZK...

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Main Authors: Lamprecht, Georg, Hsieh, Chih-Jen, Lissner, Simone, Nold, Lilia, Heil, Andreas, Gaco, Veronika, Schäfer, Julia, Turner, Jerrold R., Gregor, Michael
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Membrane Transport, Structure, Function, and Biogenesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740598/
https://ncbi.nlm.nih.gov/pubmed/19447883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.004127
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