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Structure and Biochemical Characterization of Protein Acetyltransferase from Sulfolobus solfataricus
The Sulfolobus solfataricus protein acetyltransferase (PAT) acetylates ALBA, an abundant nonspecific DNA-binding protein, on Lys(16) to reduce its DNA affinity, and the Sir2 deacetylase reverses the modification to cause transcriptional repression. This represents a “primitive” model for chromatin r...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740566/ https://ncbi.nlm.nih.gov/pubmed/19473964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.014951 |
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