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A General Method for Copper-Catalyzed Arylation of Arene C-H Bonds

A general method for copper-catalyzed arylation of sp(2) C-H bonds with pKa's below 35 has been developed. The method employs aryl halide as the coupling partner, lithium alkoxide or K(3)PO(4) base, and DMF, DMPU, or mixed DMF/xylenes solvent. A variety of electron-rich and electron-poor hetero...

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Main Authors: Do, Hien-Quang, Kashif Khan, Rana M., Daugulis, Olafs
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740489/
https://ncbi.nlm.nih.gov/pubmed/18855471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja805688p
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