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Sod2 knock-down in the musculature has whole organism consequences in Drosophila

Oxidative damage to cell macromolecules by reactive oxygen species is associated with numerous diseases and aging. In Drosophila, RNAi-mediated silencing of the mitochondrial antioxidant manganese superoxide dismutase (SOD2) throughout the body dramatically reduces life span, accelerates senescence...

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Detalhes bibliográficos
Main Authors: Martin, Ian, Jones, Melanie A., Rhodenizer, Devin, Zheng, Jie, Warrick, John M., Seroude, Laurent, Grotewiel, Mike
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739907/
https://ncbi.nlm.nih.gov/pubmed/19545620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.06.021
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