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Resonance Raman spectra of an O(2)-binding H-NOX domain reveal heme relaxation upon mutation

Resonance Raman spectra are measured for Tt H-NOX WT and three other Tt H-NOX proteins containing mutations at key conserved residues to determine the heme conformation in solution. The most dramatic changes in heme conformation occurred in the O(2)-bound forms, and the single Tt H-NOX P115A mutatio...

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Detalhes bibliográficos
Main Authors: Tran, Rosalie, Boon, Elizabeth M., Marletta, Michael A., Mathies, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739889/
https://ncbi.nlm.nih.gov/pubmed/19653642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900563g
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