Association of a genetic polymorphism (-44 C/G SNP) in the human DEFB1 gene with expression and inducibility of multiple β-defensins in gingival keratinocytes

BACKGROUND: Human β-defensins (hBDs) are antimicrobial peptides with a role in innate immune defense. Our laboratory previously showed that a single nucleotide polymorphism (SNP) in the 5' untranslated region of the hBD1 gene (DEFB1), denoted -44 (rs1800972), is correlated with protection from...

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Главные авторы: Kalus, Andrea A, Fredericks, L Page, Hacker, Beth M, Dommisch, Henrik, Presland, Richard B, Kimball, Janet R, Dale, Beverly A
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2009
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739845/
https://ncbi.nlm.nih.gov/pubmed/19712472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6831-9-21
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