Germline MutY Human Homologue Mutations and Colorectal Cancer: A Multisite Case-Control Study

BACKGROUND & AIMS: The MutY human homologue (MYH) gene is a member of the base-excision repair pathway involved in the repair of oxidative DNA damage. The objective of this study was to determine colorectal cancer (CRC) risk associated with mutations in the MYH gene. METHODS: A total of 3811 CRC...

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Huvudupphovsmän: Cleary, Sean P., Cotterchio, Michelle, Jenkins, Mark A., Kim, Hyeja, Bristow, Robert, Green, Roger, Haile, Robert, Hopper, John L., LeMarchand, Loic, Lindor, Noralane, Parfrey, Patrick, Potter, John, Younghusband, Ban, Gallinger, Steven
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739726/
https://ncbi.nlm.nih.gov/pubmed/19245865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.12.050
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