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GEC-targeted HO-1 expression reduces proteinuria in glomerular immune injury
Induction of heme oxygenase (HO)-1 is a key defense mechanism against oxidative stress. Compared with tubules, glomeruli are refractory to HO-1 upregulation in response to injury. This can be a disadvantage as it may be associated with insufficient production of cytoprotective heme-degradation metab...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Physiological Society
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739711/ https://ncbi.nlm.nih.gov/pubmed/19587144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00213.2009 |
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