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Quantification of Thyroglobulin, a Low-abundance Serum Protein, by Immunoaffinity Peptide Enrichment and Tandem Mass Spectrometry

BACKGROUND: Quantification of serum tumor markers plays an important role in determining whether patients treated for cancer require further therapy. Whereas large-scale proteomic efforts aim to identify novel tumor markers to facilitate early detection, optimization of methods for quantifying known...

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Main Authors: Hoofnagle, Andrew N., Becker, Jessica O., Wener, Mark H., Heinecke, Jay W.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739673/
https://ncbi.nlm.nih.gov/pubmed/18801935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2008.109652
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