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Designing Protease Sensors for Real-time Imaging of Trypsin Activation in Pancreatic Cancer Cells

Acute pancreatitis is a serious and potentially fatal disease caused by intracellular trypsinogen activation. Although protease detection has been greatly facilitated by the development of protease probes capable of monitoring protease activation and inhibition, real-time quantitative measurement of...

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Detalhes bibliográficos
Main Authors: Chen, Ning, Zou, Jin, Wang, Siming, Ye, Yiming, Huang, Yun, Gadda, Giovanni, Yang, Jenny J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739378/
https://ncbi.nlm.nih.gov/pubmed/19271729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802289v
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