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Effect of Zoledronic Acid on Oral Fibroblasts and Epithelial Cells: A Potential Mechanism of Bisphosphonate-Associated Osteonecrosis

Osteonecrosis of the jaw secondary to bisphosphonate infusion (zoledronic acid-ZA) is assumed to be a bone disease. The purpose of this study was to investigate the effects of ZA on soft tissues using oral mucosal cells as an in vitro model of soft tissue cell death in the pathogenesis of bone necro...

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Detalhes bibliográficos
Main Authors: Scheper, MA, Badros, A, Chaisuparat, R, Cullen, KJ, Meiller, TF
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739302/
https://ncbi.nlm.nih.gov/pubmed/19036117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2008.07504.x
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