Synergistic effects of Inward Rectifier (I(K1)) and Pacemaker (I(f)) Currents on the Induction of Bioengineered Cardiac Automaticity

INTRODUCTION: Normal heart rhythms originate in the sinoatrial node. HCN-encoded funny current (I(f)) and the Kir2-encoded inward rectifier (I(K1)) counteract each other by respectively oscillating and stabilizing the negative resting membrane potential, controlling action potential firing. Therefor...

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Main Authors: Tse, Hung-Fat, Siu, Chung-Wah, Chan, Yau-Chi, Lau, Yee-Man, Lau, Chu-Pak, Li, Ronald A.
格式: Artigo
語言:Inglês
出版: 2009
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739246/
https://ncbi.nlm.nih.gov/pubmed/19460073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1540-8167.2009.01475.x
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