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A directional Wnt/β-catenin-Sox2-proneural pathway regulates the transition from proliferation to differentiation in the Xenopus retina

Progenitor cells in the central nervous system must leave the cell cycle to become neurons and glia, but the signals that coordinate this transition remain largely unknown. We previously found that Wnt signaling, acting through Sox2, promotes neural competence in the Xenopus retina by activating pro...

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Detalhes bibliográficos
Main Authors: Agathocleous, Michalis, Iordanova, Ilina, Willardsen, Minde I., Xue, Xiao Yan, Vetter, Monica L., Harris, William A., Moore, Kathryn B.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739145/
https://ncbi.nlm.nih.gov/pubmed/19736324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.040451
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