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Axotomy-Induced Smad1 Activation Promotes Axonal Growth in Adult Sensory Neurons

Mature neurons have diminished intrinsic regenerative capacity. Axotomy of the peripheral branch of adult dorsal root ganglia (a “conditioning” lesion) triggers a transcription-dependent axon growth program. Here, we show that this growth program requires the function of the transcription factor Sma...

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Detalhes bibliográficos
Main Authors: Zou, Hongyan, Ho, Carole, Wong, Karen, Tessier-Lavigne, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739099/
https://ncbi.nlm.nih.gov/pubmed/19494134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5397-08.2009
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