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Brain Cancer Stem Cells Display Preferential Sensitivity to Akt Inhibition

Malignant brain tumors are among the most lethal cancers, and conventional therapies are largely limited to palliation. Novel therapies targeted against specific molecular pathways may offer improved efficacy and reduced toxicity compared to conventional therapies, but initial clinical trials of mol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Eyler, Christine E., Foo, Wen-Chi, LaFiura, Katherine M., McLendon, Roger E., Hjelmeland, Anita B., Rich, Jeremy N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739007/
https://ncbi.nlm.nih.gov/pubmed/18802038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2007-1073
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