Inactivation of uPA and its receptor uPAR by 3, 3'-Diindolylmethane (DIM) leads to the inhibition of Prostate Cancer Cell growth and migration

3, 3'-Diindolylmethane (DIM) has been studied for its putative anti-cancer properties, especially against prostate cancer; however, its exact mechanism of action remains unclear. We recently provided preliminary data suggesting down-regulation of uPA during B-DIM (a clinically active DIM)-induc...

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Bibliographische Detailangaben
Hauptverfasser: Ahmad, Aamir, Kong, Dejuan, Sarkar, Sanila H., Wang, Zhiwei, Banerjee, Sanjeev, Sarkar, Fazlul H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738995/
https://ncbi.nlm.nih.gov/pubmed/19330806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22152
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