Convergent patterns of association between phenylalanine hydroxylase variants and schizophrenia in four independent samples

Recessive mutations in the Phenylalanine hydroxylase (PAH) gene predispose to phenylketonuria (PKU) in conjunction with dietary exposure to phenylalanine. Previous studies have suggested PAH variations could confer risk for schizophrenia, but comprehensive follow-up has not been reported. We analyze...

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Main Authors: Talkowski, Michael E., McClain, Lora, Allen, Trina, Bradford, L. DiAnne, Calkins, Monica, Edwards, Neil, Georgieva, Lyudmila, Go, Rodney, Gur, Ruben, Gur, Raquel, Kirov, George, Chowdari, Kodavali, Kwentus, Joseph, Lyons, Paul, Mansour, Hader, McEvoy, Joseph, O’ Donovan, Michael C., O’Jile, Judith, Owen, Michael J., Santos, Alberto, Savage, Robert, Toncheva, Draga, Vockley, Gerard, Wood, Joel, Devlin, Bernie, Nimgaonkar, Vishwajit L.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738981/
https://ncbi.nlm.nih.gov/pubmed/18937293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.30862
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