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Estrogen downregulates the proximal tubule type IIa sodium phosphate cotransporter causing phosphate wasting and hypophosphatemia

Estrogen treatment causes significant hypophosphatemia in patients. To determine the mechanisms responsible for this effect, we injected ovariectomized rats with either 17β-estradiol or vehicle for three days. Significant renal phosphate wasting and hypophosphatemia occurred in estrogen-treated rats...

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Bibliografiske detaljer
Main Authors: Faroqui, S, Levi, M, Soleimani, M, Amlal, H
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738940/
https://ncbi.nlm.nih.gov/pubmed/18305465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2008.33
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