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Genistein Inhibition of Topoisomerase IIα Expression Participated by Sp1 and Sp3 in HeLa Cell

Genistein (4′, 5, 7-trihydroxyisoflavone) is an isoflavone compound obtained from plants that has potential applications in cancer therapy. However, the molecular mechanism of the action of genistein on cancer cell apoptosis is not well known. In this study, we investigated the effect of genistein o...

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Dettagli Bibliografici
Autori principali: Zhou, Najing, Yan, Yunli, Li, Wenling, Wang, Yanling, Zheng, Lifen, Han, Shuo, Yan, Yongxin, Li, Yunzhi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Molecular Diversity Preservation International (MDPI) 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738924/
https://ncbi.nlm.nih.gov/pubmed/19742137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms10073255
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