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Genistein Inhibition of Topoisomerase IIα Expression Participated by Sp1 and Sp3 in HeLa Cell

Genistein (4′, 5, 7-trihydroxyisoflavone) is an isoflavone compound obtained from plants that has potential applications in cancer therapy. However, the molecular mechanism of the action of genistein on cancer cell apoptosis is not well known. In this study, we investigated the effect of genistein o...

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Detalhes bibliográficos
Main Authors: Zhou, Najing, Yan, Yunli, Li, Wenling, Wang, Yanling, Zheng, Lifen, Han, Shuo, Yan, Yongxin, Li, Yunzhi
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738924/
https://ncbi.nlm.nih.gov/pubmed/19742137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms10073255
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