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Genistein Inhibition of Topoisomerase IIα Expression Participated by Sp1 and Sp3 in HeLa Cell

Genistein (4′, 5, 7-trihydroxyisoflavone) is an isoflavone compound obtained from plants that has potential applications in cancer therapy. However, the molecular mechanism of the action of genistein on cancer cell apoptosis is not well known. In this study, we investigated the effect of genistein o...

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Bibliografiske detaljer
Main Authors: Zhou, Najing, Yan, Yunli, Li, Wenling, Wang, Yanling, Zheng, Lifen, Han, Shuo, Yan, Yongxin, Li, Yunzhi
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Diversity Preservation International (MDPI) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738924/
https://ncbi.nlm.nih.gov/pubmed/19742137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms10073255
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