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Effect of Seven Newly Synthesized and Currently Available Oxime Cholinesterase Reactivators on Cyclosarin-Intoxicated Rats

Seven new oxime-based acetylcholinesterase reactivators were compared with three currently available ones (obidoxime, trimedoxime, HI-6) for their ability to lessen cholinesterase inhibition in blood and brain of cyclosarin-treated rats. Oximes were given at doses of 5% their LD(50) along with 21 mg...

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Hlavní autoři: Karasova, Jana Zdarova, Kassa, Jiri, Musilek, Kamil, Pohanka, Miroslav, Novotny, Ladislav, Kuca, Kamil
Médium: Artigo
Jazyk:Inglês
Vydáno: Molecular Diversity Preservation International (MDPI) 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738912/
https://ncbi.nlm.nih.gov/pubmed/19742125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms10073065
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