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Lack of nitrate tolerance in isosorbide dinitrate- and sodium nitroprusside-induced relaxation of rabbit internal anal sphincter

AIM: To investigate the tolerance development against the relaxant effect of nitric oxide donating drug isosorbide dinitrate (ISDN) and sodium nitroprusside (SNP) in internal anal sphincter (IAS) smooth muscle. METHODS: Relaxation responses of ISDN, and electrical field stimulation (EFS) were obtain...

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Bibliografski detalji
Glavni autori: Koyuncu, Ayhan, Bagcivan, Ihsan, Sarac, Bulent, Aydin, Cengiz, Yildirim, Sahin, Sarioglu, Yusuf
Format: Artigo
Jezik:Inglês
Izdano: The WJG Press and Baishideng 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738791/
https://ncbi.nlm.nih.gov/pubmed/18698681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.4667
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