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Disruption of Th2 immunity results in a gender specific expansion of IL-13 producing accessory Natural Killer cells during helminth infection

Host gender has previously been identified as a determining factor in the resolution of Trichuris muris infection in mice lacking Interleukin-4 (IL-4KO BALB/c). Worm expulsion in these mice is delayed, but occurs in females. In this study we were able to demonstrate delayed expulsion occurs at day 2...

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Autori principali: Hepworth, Matthew R., Grencis, Richard K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738657/
https://ncbi.nlm.nih.gov/pubmed/19692641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900577
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