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Limited terminal transferase in human DNA polymerase μ defines the required balance between accuracy and efficiency in NHEJ
DNA polymerase mu (Polμ) is a family X member implicated in DNA repair, with template-directed and terminal transferase (template-independent) activities. It has been proposed that the terminal transferase activity of Polμ can be specifically required during non-homologous end joining (NHEJ) to crea...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2738622/ https://ncbi.nlm.nih.gov/pubmed/19805281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908492106 |
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