A comparison of neurocognitive functioning in children previously randomized to dexamethasone or prednisone in the treatment of childhood acute lymphoblastic leukemia

In previous clinical trials of childhood acute lymphoblastic leukemia (ALL), dexamethasone resulted in higher event-free survival rates than prednisone, presumably due to greater central nervous system penetration. Dexamethasone's association with long-term neurocognitive toxicity is unknown. I...

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Detalhes bibliográficos
Main Authors: Kadan-Lottick, Nina S., Brouwers, Pim, Breiger, David, Kaleita, Thomas, Dziura, James, Liu, Haibei, Chen, Lu, Nicoletti, Megan, Stork, Linda, Bostrom, Bruce, Neglia, Joseph P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738566/
https://ncbi.nlm.nih.gov/pubmed/19546477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-186502
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