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A Novel Scoring Approach for Protein Co-Purification Data Reveals High Interaction Specificity
Large-scale protein interaction networks (PINs) have typically been discerned using affinity purification followed by mass spectrometry (AP/MS) and yeast two-hybrid (Y2H) techniques. It is generally recognized that Y2H screens detect direct binary interactions while the AP/MS method captures co-comp...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2738424/ https://ncbi.nlm.nih.gov/pubmed/19779545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000515 |
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