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HOXA9 Modulates Its Oncogenic Partner Meis1 To Influence Normal Hematopoiesis

While investigating the mechanism of action of the HOXA9 protein, we serendipitously identified Meis1 as a HOXA9 regulatory target. Since HOXA9 and MEIS1 play key developmental roles, are cooperating DNA binding proteins and leukemic oncoproteins, and are important for normal hematopoiesis, the regu...

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Bibliografski detalji
Glavni autori: Hu, Yu-Long, Fong, Steve, Ferrell, Christina, Largman, Corey, Shen, Wei-Fang
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738281/
https://ncbi.nlm.nih.gov/pubmed/19620287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00545-09
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