Protective and Pathologic Roles of the Immune Response to Mouse Hepatitis Virus Type 1: Implications for Severe Acute Respiratory Syndrome

Intranasal mouse hepatitis virus type 1 (MHV-1) infection of mice induces lung pathology similar to that observed in severe acute respiratory syndrome (SARS) patients. However, the severity of MHV-1-induced pulmonary disease varies among mouse strains, and it has been suggested that differences in t...

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Bibliographic Details
Main Authors: Khanolkar, Aaruni, Hartwig, Stacey M., Haag, Brayton A., Meyerholz, David K., Epping, Lecia L., Haring, Jodie S., Varga, Steven M., Harty, John T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738266/
https://ncbi.nlm.nih.gov/pubmed/19570864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00355-09
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