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Impact of Quaternary Organization on the Antigenic Structure of the Tick-Borne Encephalitis Virus Envelope Glycoprotein E

The envelope protein E of flaviviruses mediates both receptor-binding and membrane fusion. At the virion surface, 180 copies of E are tightly packed and organized in a herringbone-like icosahedral structure, whereas in noninfectious subviral particles, 60 copies are arranged in a T=1 icosahedral sym...

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Autors principals: Kiermayr, Stefan, Stiasny, Karin, Heinz, Franz X.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738186/
https://ncbi.nlm.nih.gov/pubmed/19553320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00660-09
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