The Infectious Molecular Clone and Pseudotyped Virus Models of Human Immunodeficiency Virus Type 1 Exhibit Significant Differences in Virion Composition with Only Moderate Differences in Infectivity and Inhibition Sensitivity

Two frequently employed methods for generating well-characterized, genetically defined infectious human immunodeficiency virus type 1 in vitro include the use of infectious molecular clones (IMCs) and pseudoviruses (PVs) competent for single-round infection. We compared six matched pairs of IMCs and...

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Detalhes bibliográficos
Main Authors: Provine, Nicholas M., Puryear, Wendy Blay, Wu, Xueling, Overbaugh, Julie, Haigwood, Nancy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738156/
https://ncbi.nlm.nih.gov/pubmed/19535443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00423-09
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