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Detection of Low Levels of Human Immunodeficiency Virus (HIV) May Be Critical for Early Diagnosis of Pediatric HIV Infection by Use of Dried Blood Spots

We compared a DNA-based assay with a total nucleic acid-based assay for early detection of infant human immunodeficiency virus (HIV) infection. The codetection of DNA and RNA did not result in an overall higher sensitivity compared to that of DNA alone. Discordant results were associated with low le...

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Detalhes bibliográficos
Main Authors: Walter, Jan, Kuhn, Louise, Semrau, Katherine, Decker, Don W., Sinkala, Moses, Kankasa, Chipepo, Thea, Donald M., Bulterys, Marc, Ou, Chin-Yih, Aldrovandi, Grace M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738105/
https://ncbi.nlm.nih.gov/pubmed/19625479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02453-08
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