Injection of Staphylococcus aureus EDIN by the Bacillus anthracis Protective Antigen Machinery Induces Vascular Permeability

Systemic injection of Bacillus anthracis lethal toxin (LT) produces vascular leakage and animal death. Recent studies suggest that LT triggers direct endothelial cell cytotoxicity that is responsible for the vascular leakage. LT is composed of heptamers of protective antigen (PA), which drives the e...

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Autori principali: Rolando, Monica, Munro, Patrick, Stefani, Caroline, Auberger, Patrick, Flatau, Gilles, Lemichez, Emmanuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2009
Soggetti:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738014/
https://ncbi.nlm.nih.gov/pubmed/19546197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00186-09
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