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Transmembrane Tumor Necrosis Factor Alpha Is Required for Enteropathy and Is Sufficient To Promote Parasite Expulsion in Gastrointestinal Helminth Infection

To study the specific role of transmembrane tumor necrosis factor (tmTNF) in protective and pathological responses against the gastrointestinal helminth Trichinella spiralis, we compared the immune responses of TNF-α/lymphotoxin alpha (LTα)(−/−) mice expressing noncleavable transgenic tmTNF to those...

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Detalles Bibliográficos
Autores principales: Ierna, M. X., Scales, H. E., Mueller, C., Lawrence, C. E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737992/
https://ncbi.nlm.nih.gov/pubmed/19564380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01461-08
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