Population Pharmacokinetics of Linezolid in Adults with Pulmonary Tuberculosis

Nineteen adults with pulmonary tuberculosis received linezolid (600 mg) once or twice daily in an early bactericidal activity trial. A one-compartment population model produced median values for the absorption rate constant, volume of distribution, and elimination rate constant of 1.5 h(−1), 29.6 li...

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Detalhes bibliográficos
Main Authors: McGee, Bryan, Dietze, Reynaldo, Hadad, David Jamil, Molino, Lucilia Pereira Dutra, Maciel, Ethel Leonor Noia, Boom, W. Henry, Palaci, Moises, Johnson, John L., Peloquin, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737850/
https://ncbi.nlm.nih.gov/pubmed/19564361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01378-08
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