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Influence of Recombination on Development of Mutational Resistance to Linezolid in Enterococcus faecalis JH2-2

We compared the propensities of Enterococcus faecalis JH2-2 and of the recombination-deficient JH2-2 recA strain to develop mutational resistance to linezolid. In both organisms, a mutation in a single rrl copy conferred resistance to linezolid. Delay in acquisition of the mutation by other rrl copi...

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Autors principals: Boumghar-Bourtchaï, Leyla, Dhalluin, Anne, Malbruny, Brigitte, Galopin, Sébastien, Leclercq, Roland
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737844/
https://ncbi.nlm.nih.gov/pubmed/19546366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01633-08
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