Suppressive and proinflammatory roles for IL-4 in the pathogenesis of experimental DILI

The pathogenesis of immune-mediated drug-induced liver injury (DILI) following halogenated anesthetics, carbamazepine, or alcohol has not been fully elucidated. Detecting cytochrome P4502E1 (CYP2E1) IgG4 autoantibodies in anesthetic DILI patients suggests a role for interleukin IL-4 in this hapten-m...

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Main Authors: Njoku, Dolores B., Li, Zhaoxia, Washington, Nicole D., Mellerson, Jenelle L., Talor, Monica V., Sharma, Rajni, Rose, Noel R.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737704/
https://ncbi.nlm.nih.gov/pubmed/19499520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838135
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