A carregar...

To scale or not to scale: the principles of dose extrapolation

The principles of inter-species dose extrapolation are poorly understood and applied. We provide an overview of the principles underlying dose scaling for size and dose adjustment for size-independent differences. Scaling of a dose is required in three main situations: the anticipation of first-in-h...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Sharma, Vijay, McNeill, John H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737649/
https://ncbi.nlm.nih.gov/pubmed/19508398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00267.x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!