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Sumoylation Regulates Nuclear Localization of Lipin-1α in Neuronal Cells

Lipin-1 is a protein that has dual functions as a phosphatidic acid phosphohydrolase (PAP) and a nuclear transcriptional coactivator. It remains unknown how the nuclear localization and coactivator functions of lipin-1 are regulated. Here, we show that lipin-1 (including both the alpha and beta isof...

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Détails bibliographiques
Auteurs principaux: Liu, Guang-Hui, Gerace, Larry
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737637/
https://ncbi.nlm.nih.gov/pubmed/19753306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007031
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