Molecular Basis of Rare Aminoglycoside Susceptibility and Pathogenesis of Burkholderia pseudomallei Clinical Isolates from Thailand

BACKGROUND: Burkholderia pseudomallei is intrinsically resistant to aminoglycosides and macrolides, mostly due to AmrAB-OprA efflux pump expression. We investigated the molecular mechanisms of aminoglycoside susceptibility exhibited by Thai strains 708a, 2188a, and 3799a. METHODOLOGY/PRINCIPAL FINDI...

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Detalhes bibliográficos
Main Authors: Trunck, Lily A., Propst, Katie L., Wuthiekanun, Vanaporn, Tuanyok, Apichai, Beckstrom-Sternberg, Stephen M., Beckstrom-Sternberg, James S., Peacock, Sharon J., Keim, Paul, Dow, Steven W., Schweizer, Herbert P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737630/
https://ncbi.nlm.nih.gov/pubmed/19771149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000519
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