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Inhibition of WNT Signaling by G Protein-Coupled Receptor (GPCR) Kinase 2 (GRK2)

Activation of Wnt signaling pathways causes release and stabilization of the transcription regulator β-catenin from a destruction complex composed of axin and the adenomatous polyposis coli (APC) protein (canonical signaling pathway). Assembly of this complex is facilitated by a protein-protein inte...

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Detalhes bibliográficos
Main Authors: Wang, Liming, Gesty-Palmer, Diane, Fields, Timothy A., Spurney, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737558/
https://ncbi.nlm.nih.gov/pubmed/19556343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0084
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