Interaction of Polysialic Acid with CCL21 Regulates the Migratory Capacity of Human Dendritic Cells

Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs). Immature DCs (iDCs) are situated in the periphery where they capture pathogen. Subsequently, they migrate as mature DCs (mDCs) to draining lymph nodes to activate T cells. CCR7 and CCL21 contribute to the migratory capacity o...

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Main Authors: Bax, Marieke, van Vliet, Sandra J., Litjens, Manja, García-Vallejo, Juan J., van Kooyk, Yvette
格式: Artigo
語言:Inglês
出版: Public Library of Science 2009
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737307/
https://ncbi.nlm.nih.gov/pubmed/19750015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006987
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