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Manganese Exposure is Cytotoxic and Alters Dopaminergic and GABAergic Neurons within the Basal Ganglia

Manganese is an essential nutrient, integral to proper metabolism of amino acids, proteins and lipids. Excessive environmental exposure to manganese can produce extrapyramidal symptoms similar to those observed in Parkinson’s disease (PD). We used in vivo and in vitro models to examine cellular and...

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Detalhes bibliográficos
Main Authors: Stanwood, Gregg D., Leitch, Duncan B., Savchenko, Valentina, Wu, Jane, Fitsanakis, Vanessa A., Anderson, Douglas J., Stankowski, Jeannette N., Aschner, Michael, McLaughlin, BethAnn
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737271/
https://ncbi.nlm.nih.gov/pubmed/19457100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06145.x
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