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PACAP-mediated ATP release from rat urothelium and regulation of PACAP/VIP and receptor mRNA in micturition pathways after cyclophosphamide (CYP)-induced cystitis

PACAP peptides are expressed in micturition pathways and PACAP expression is regulated by urinary bladder inflammation. Previous physiological studies have demonstrated roles for PACAP27 and PACAP38 in detrusor smooth muscle (DSM) contraction and a PAC(1) receptor antagonist reduced cyclophosphamide...

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Détails bibliographiques
Auteurs principaux: Girard, Beatrice M., Wolf-Johnston, Amanda, Braas, Karen M., Birder, Lori A., May, Victor, Vizzard, Margaret A.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737258/
https://ncbi.nlm.nih.gov/pubmed/18563302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-008-9104-4
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