Delivery of RNAi reagents in murine models of obesity and diabetes

RNA interference (RNAi) is an exciting new tool to effect acute in vivo knockdown of genes for pharmacological target validation. Testing the application of this technology to metabolic disease targets, three RNAi delivery methods were compared in two frequently utilized preclinical models of obesit...

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Detalhes bibliográficos
Main Authors: Wilcox, Denise M, Yang, Ruojing, Morgan, Sherry J, Nguyen, Phong T, Voorbach, Martin J, Jung, Paul M, Haasch, Deanna L, Lin, Emily, Bush, Eugene N, Opgenorth, Terry J, Jacobson, Peer B, Collins, Christine A, Rondinone, Cristina M, Surowy, Terry, Landschulz, Katherine T
Formato: Artigo
Idioma:Inglês
Publicado em: Library Publishing Media 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737213/
https://ncbi.nlm.nih.gov/pubmed/19771218
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