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The Toll-Like receptor adaptor TRIF contributes to otitis media pathogenesis and recovery

BACKGROUND: Toll-like receptor (TLR) signalling is crucial for innate immune responses to infection. The involvement of TLRs in otitis media (OM), the most prevalent childhood disease in developed countries, has been implicated by studies in middle ear cell lines, by association studies of TLR-relat...

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Detalhes bibliográficos
Main Authors: Leichtle, Anke, Hernandez, Michelle, Pak, Kwang, Webster, Nicholas J, Wasserman, Stephen I, Ryan, Allen F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736931/
https://ncbi.nlm.nih.gov/pubmed/19656404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-10-45
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