An Injectable and In Situ-Gelling Biopolymer for Sustained Drug Release Following Perineural Administration

STUDY DESIGN: This study evaluated whether the aggregation behavior of a thermally responsive elastin-like polypeptide (ELP) prolongs protein residence time at the dorsal root ganglion (DRG). This work involves development of a sustained-release drug delivery vehicle to provide high and sustained le...

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Bibliographic Details
Main Authors: Shamji, Mohammed F., Whitlatch, Lyman, Friedman, Allan H., Richardson, William J., Chilkoti, Ashutosh, Setton, Lori A.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736879/
https://ncbi.nlm.nih.gov/pubmed/18379401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/BRS.0b013e3181695773
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