Oncolytic activity of Sindbis virus in human oral squamous carcinoma cells

BACKGROUND: Sindbis virus (SIN) infection causes no or only mild symptoms (fever, rash, and arthralgia) in humans. However, SIN has a strong cytopathic effect (CPE) on various cancer cells. This study focuses on the oncolytic activity of SIN AR399 on oral cancer cells compared with reovirus, a well-...

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Detalhes bibliográficos
Main Authors: Saito, K, Uzawa, K, Kasamatsu, A, Shinozuka, K, Sakuma, K, Yamatoji, M, Shiiba, M, Shino, Y, Shirasawa, H, Tanzawa, H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736826/
https://ncbi.nlm.nih.gov/pubmed/19638980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605209
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